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An observational analysis of 55 alcoholics with TB found that light liver impairment in alcoholics is not a contraindication for treatment with ethionamide . On the 55 patients for the reason that review, 30 received ethionamide and three patients developed parenchymal liver destruction. Two of these cases may have been related to the concurrent use of pyrazinamide . First-line treatment of pulmonary tuberculosis entails an initial stage of four agents .


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Weighing 8 kg-1 teaspoonful 4 times a day for 14 to 21 times. Weighing 16 kg-2 teaspoonfuls or 1 tablet 4 times every day for 14 to 21 days. Weighing 24 kg-3 teaspoonfuls or 1 ½ tablets 4 times every day for 14 to 21 times. Weighing 32 kg-4 teaspoonfuls or 2 tablets 4 times each day for 14 to 21 days. Weighing 40 kg-5 teaspoonfuls or 2 ½ tablets 4 times each day for 14 to 21 times.

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